American Journal of Nursing Research. 2019, 7(3), 387-391
DOI: 10.12691/AJNR-7-3-20
Original Research

Effect of Positive End Expiratory Pressure on Central Venous Pressure in Mechanically Ventilated Patients

Khaled Mohammed Al-Sayaghi1, 2, , Hassnaa Eid Shaban Mosa3, Masouda Hassan Atrous4, Azza Hamdi El-Soussi5, Ahmed Youssef Ali6 and Sahar Hossni El-shenawi5

1Critical Care and Emergency Nursing, College of Nursing, Taibah University, KSA

2Critical Care and Emergency Nursing, Faculty of Medicine and Health Sciences, Sana'a University, Yemen

3Medical Surgical Nursing, Faculty of Nursing, Menoufia University, Egypt

4Critical Care and Emergency Nursing, Faculty of Nursing, Jouf University, KSA

5Critical Care and Emergency Nursing, Critical Care and Emergency Nursing Department, Faculty of Nursing, Alexandria University, Egypt

6Anesthesia and Surgical Intensive Care, Faculty of Medicine, Alexandria University, Egypt

Pub. Date: April 24, 2019

Cite this paper

Khaled Mohammed Al-Sayaghi, Hassnaa Eid Shaban Mosa, Masouda Hassan Atrous, Azza Hamdi El-Soussi, Ahmed Youssef Ali and Sahar Hossni El-shenawi. Effect of Positive End Expiratory Pressure on Central Venous Pressure in Mechanically Ventilated Patients. American Journal of Nursing Research. 2019; 7(3):387-391. doi: 10.12691/AJNR-7-3-20


Background: Central venous pressure (CVP) monitoring remains in common use as an index of circulatory filling and cardiac preload. Positive end-expiratory pressure (PEEP) in mechanically ventilated patients can affect CVP via increasing intra-thoracic pressure. Critical care nurses should be able to measure the CVP competently and identify the factors affecting its readings. Aim: The current study was conducted to determine the effect of PEEP on the CVP readings in mechanically ventilated patients. Methods: a descriptive design used in this study. A convenient sample of 200 adult critically ill patients of both sex, hemodynamically and respiratory stable, having a central venous catheter (CVC) in place, and attached to a mechanical ventilator and pulse oximeter were included in the study. The patient's baseline CVP was recorded while the patient connected to the mechanical ventilator, then the patients were temporary disconnected from the mechanical ventilator and the CVP measured again without the effect of PEEP. Results: About 40% of the study sample aged 45 to 64 years, 52.5% were males, 50 % suffered from respiratory disorders, and 49% were overhydrated. Eighty eight percent of the study sample was on PEEP levels between 5 to < 10 cmH2O. The CVP readings while the patients connected to MV were higher than CVP reading while the patients without PEEP, but these differences were not significant. Conclusion: CVP readings are not significant affected by the PEEP up to 15 cmH2O. The CVP can be reliably measured while patients are connected to MV. Recommendations: Measurement of CVP can be obtained while the patient is connected to MV.


PEEP, mechanical ventilation, central venous pressure, critically ill patients


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